Posts Tagged 'biomarkers'
Significance of FFPE Tissue Samples in Preventive Genomics and Precision Medicine
Formalin-fixed paraffin-embedded (FFPE) tissues can play a transformative role in preventive genomics and precision medicine. Analysis of DNA and RNA are central to our understanding of disease and disease risk. With FFPE tissues, these biomolecules (and other essential characteristics) are available for scientists to study. The longevity of FFPE tissue samples and their long history…
Read MoreAdvancing Biospecimen Procurement with Cutting-edge Technologies
Imagine a world where diseases can be prevented before they even occur, where medications are tailored specifically to each individual’s genetic makeup, and where new drugs are developed at an unprecedented rate. This future is quickly becoming a reality due to the rapid evolution in technologies the field of biospecimen procurement has witnessed over the…
Read MoreStandardized Preanalytical Coding (SPREC) in Tissue Biobanking
Tissue biobanking involves the collection, processing, storage, and study of biospecimens, such as human biofluids and solid tissue samples1. High biospecimen quality and collection of relevant patient data allow researchers and clinicians to tailor a personalized treatment for a given patient. Furthermore, biobanking allows researchers to assess differences by race and ethnicity for the patient…
Read MoreCancer Statistics, History of Blood Cancer, and the Role of Biobanking
Introduction According to the World Health Organization (WHO), cancer accounted for nearly 10 million deaths worldwide in 2020 alone.1 This devastating disease can affect any part of the body, occurring when abnormal cells become dysregulated and begin to grow and spread uncontrollably. However, to fully recognize its burden and succeed in cancer research, we must…
Read MoreHow Biomarker Discovery and Validation Supports Targeted Cancer Therapies
Biomarkers are essential tools in oncology research, allowing for early detection, diagnosis, and personalized cancer treatment.1 For this reason, driving innovation in biomarker discovery and validation is critical for developing targeted therapies to improve clinical outcomes. Here, we discuss the concept of biomarkers in the field of oncology and why they have been indispensable to the…
Read MoreFresh Cancer Tissue Samples – Applications in Biomedical Research
Today, an important research segment of cancer research is interested in fresh cancer tissue samples to extract a particular cell type or molecule or to test the effects of a particular drug or innovative therapy. This biospecimen type offers a mutitude of applications for the most innovative stuidies and projects. Before researchers delved into the in…
Read MoreHow Biospecimens Support Biomarkers Development?
One of the main applications of human-derived biosamples in biomedical research is in the discovery and validation of new biomarkers. This is especially true for the oncology field, where biospecimens support biomarkers development from the discovery stage through validation, and ultimately during implementation into diagnostics and choice of targeted therapy by providing scientists and clinicians…
Read More