Posts Tagged 'biofluids'
Introduction According to the World Health Organization (WHO), cancer accounted for nearly 10 million deaths worldwide in 2020 alone.1 This devastating disease can affect any part of the body, occurring when abnormal cells become dysregulated and begin to grow and spread uncontrollably. However, to fully recognize its burden and succeed in cancer research, we must…Read More
Biomarkers are essential tools in oncology research, allowing for early detection, diagnosis, and personalized cancer treatment.1 For this reason, driving innovation in biomarker discovery and validation is critical for developing targeted therapies to improve clinical outcomes. Here, we discuss the concept of biomarkers in the field of oncology and why they have been indispensable to the…Read More
The Tumor Microenvironment (TME) is the complex, heterogeneous cellular environment surrounding a tumor. The TME contains immune and inflammatory cells, blood vessels, fibroblasts and myofibroblasts, extracellular matrix (ECM), and a vast array of signaling molecules 1. The dynamic interactions between tumor cells and the TME largely determine whether the primary tumor metastasizes (develops secondary…Read More
The term peripheral blood corresponds to all the blood circulating through the body’s blood vessel system and not concentrated within a specific organ (e.g. liver, spleen). Peripheral blood processing and analysis is a routine in clinical practice. However, the increasing number of translational research and life-saving therapies based on blood analysis, biobanking manipulation, and transfusion…Read More
December 2, 2020 How to choose the right biospecimen is a critical question upfront of every biospecimen collection project. Taking the time to answer it can prevent both time and financial losses and guarantee the success of your study. It is important to select the type and format that best fits your project’s final goals. The…Read More