Posts Tagged 'tme'

  The Tumor Microenvironment (TME) is the complex, heterogeneous cellular environment surrounding a tumor. The TME contains immune and inflammatory cells, blood vessels, fibroblasts and myofibroblasts, extracellular matrix (ECM), and a vast array of signaling molecules 1. The dynamic interactions between tumor cells and the TME largely determine whether the primary tumor metastasizes (develops secondary…