Importance and Applications of Fresh Cancer Tissue Samples for Biomedical Research

Before researchers delved into the in vitro manipulation of fresh tissues, biospecimens were collected and stored in biorepositories for an indefinite period of time. To make this long-term storage possible, biosamples needed to be preserved. Although these methods are still needed and used, the expansion of innovative biomedical research has reshaped the static nature of…

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Discovery, Validation and Use of Cancer Biomarkers — Current Trends and Obstacles

When we speak about the role of biospecimens in the advancement of personalized precision medicine, we can’t avoid the topic of biomarkers. The term biomarker indicates a molecular signature (DNA, RNA, protein, lipid, metabolite) that can be objectively measured. Its levels are an indication of a normal physiological process, an abnormal pathological condition, or a…

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The Biobanking Space Is Attracting Investors and Media Interest

In about three and half months after launching a crowdfunding campaign on MicroVentures.com, an Austin, TX-based online equity crowdfunding platform, investments in Audubon Bioscience total nearly $220,000 from over 440 investors. The success of the crowdfunding campaign is a strong demonstration of the recognition the biobanking space is gaining as a key component for today’s…

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Medical Staff’s Role in Biospecimen Procurement

Biospecimens are being largely recognized as a crucial element for developing biomarker-based, targeted therapies and diagnostics. While essential to biomedical research advancement, biospecimen procurement is also a complex process involving the well-coordinated efforts of various players 1,2. This multiplayer nature of biobanking creates a certain degree of disconnection and often leaves the different parties with…

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What is Biobanking? An Overview of a Fast-Growing Field

Novel therapies are moving away from the “one size fits all” concept and are working towards a patient-tailored precision therapy approach 1. Since this transition relies on patient-derived biosamples, it has strongly reshaped the field of biobanking and biospecimens procurement 2,3. The importance of studying both liquid and solid human bioproducts lies within the samples’…

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The Universe Within a Blood Tube – Peripheral Blood and Its Components

The term peripheral blood corresponds to all the blood circulating through the body’s blood vessel system and not concentrated within a specific organ (e.g. liver, spleen). While peripheral blood analysis is a classic routine in clinical healthcare practice, its vast number of molecules and cellular components and the relatively easy and non-invasive collection method make…

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5 Good Practices for Handling Blood Samples

Blood in a collection tube

  While peripheral blood and its precious sub-components are gaining growing attention from the biomedical research field, an increasing body of evidence 1,2  shows that even small changes in the pre-analytical conditions may affect sample quality and integrity. These observations drive the urgent need for establishing good practices and unified protocols for blood sample collection,…

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