Posts Tagged 'biospecimens procurement'

Cell Lines Versus Primary Cells as In Vitro Disease Models – An Overview

Cell lines and primary cells as in vitro disease models.

For decades, research labs around the world have been using cancer cell lines as the in vitro disease model of choice. And while biomedical and biopharma research have accomplished impressive achievements and provided a plethora of new insights into disease mechanisms and innovative treatments, they also outlined the persistent challenges and limitations translational research is…

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Biospecimens in Personalized Medicine – from Promise to Reality

Biospecimens are crucial for turning personalized medicine's promise into a reality

Biospecimens in personalized medicine are a cornerstone for its future development and establishment as a real-life clinical practice. And yet, the crucial role of biosamples and the process of their ethical collection are not well understood. As a biospecimen provider, we consider it part of our mission to educate and raise awareness on this topic.  …

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Plasma Matched Biosample Sets – a Key Component of Audubon’s 2020 Collections

lasma emerges as a key component of matched biosample sets in our 2020 biospecimen collections.

Based on our yearly analysis of collection requests and projects, we noticed that plasma matched biosample sets were a considerable part of our work over the last year.  At Audubon Bioscience, we work closely with our scientific partners to provide a personalized relationship by having specific collection methods based on their research needs, ensuring quality…

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Fresh Cancer Tissue Samples – Applications in Biomedical Research

Fresh cancer tissue samples are becoming a leading biospecimen for innovative biomedical research.

Today, an important research segment of cancer research is interested in fresh cancer tissue samples to extract a particular cell type or molecule or to test the effects of a particular drug or innovative therapy. This biospecimen type offers a mutitude of applications for the most innovative stuidies and projects.  Before researchers delved into the in…

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How Biospecimens Support Biomarkers Development?

Biospecimens support cancer biomarkers discovery and use for the development of life-saving therapies.

One of the main applications of human-derived biosamples in biomedical research is in the discovery and validation of new biomarkers. This is especially true for the oncology field, where biospecimens support biomarkers development from the discovery stage through validation, and ultimately during implementation into diagnostics and choice of targeted therapy by providing scientists and clinicians…

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The Biobanking Space Is Attracting Investors and Media

Biobanking is attracting investors and media interest, showcasing the increasing appreciation towards the field.

The observation that biobanking is attracting investors and media attention strongly confirms the critical role of the field in the modern biotech and biopharma industries and global healthcare advancements. In about three and half months after launching a crowdfunding campaign on MicroVentures.com, an Austin, TX-based online equity crowdfunding platform, investments in Audubon Bioscience total nearly…

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Medical Staff’s Role in Biospecimen Procurement

Medical staff play a crucial role in the porcess of biospecimen procurement.

Medical staff’s role in biospecimen procurement is a key factor for the development and conduct of this field. Yet, it often ramains largely misread. Biospecimens are being largely recognized as a crucial element for developing biomarker-based, targeted therapies and diagnostics. While essential to biomedical research advancement, biospecimen procurement is also a complex process involving the…

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What is Biobanking? An Overview of a Fast-Growing Field

An overview of the biobanking field.

Novel therapies are moving away from the “one size fits all” concept and are working towards a patient-tailored precision therapy approach 1. Since this transition relies on patient-derived biosamples, it has strongly reshaped the field of biobanking and biospecimens procurement 2,3. The importance of studying both liquid and solid human bioproducts lies within the samples’…

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Peripheral Blood Processing – Discover The Universe Within a Blood Tube

Peripheral blood processing methods allow to subfraction and analyze the various subcomponents of whole blood.

The term peripheral blood corresponds to all the blood circulating through the body’s blood vessel system and not concentrated within a specific organ (e.g. liver, spleen). Peripheral blood processing and analysis is a routine in clinical practice. However, the increasing number of translational research and life-saving therapies based on blood analysis, biobanking manipulation, and transfusion…

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FFPE or Frozen Tissue – How to Choose Between Their Pros and Cons?

FFPE or frozen tissue have a list of advantages and limitations to be considered to reply to the downstream analytical purposes of your solid tissue biospecimen collection.

  FFPE or frozen tissue is a very common question during the initial design of a solid tissue collection project. Preserved human solid tissue comes in two forms – Formalin-Fixed Paraffin-Embedded (FFPE) or snap-frozen. Both methods have their advantages and disadvantages, and choosing one over the other depends on the study’s needs and methodology. Here,…

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